USMLE Step 1 Question of the day #79

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Questions:

Pharmacology
1. What is the musculoskeletal toxicity of fibrates?

Hematology/oncology
2. _______ Proteinuria in Multiple Myeloma is due to free amyloid light chains in circulation that end up in the urine.

Musculoskeletal, Skin, Connective Tissue
3. _______ is a type of epithelial cell junction that is also known as Zonula Adherens.

Neurology
4. What is an uncal herniation?

Microbiology
5. What is the etiology of Tinea Versicolour?

Answers:

1. What is the musculoskeletal toxicity of fibrates?
A: Myopathy

2. _______ Proteinuria in Multiple Myeloma is due to free amyloid light chains in circulation that end up in the urine.
A; Bence Jones
These light chains can also cause renal failure; i.e. Myeloma Kidney

3. _______ is a type of epithelial cell junction that is also known as Zonula Adherens.
A: Adherens Junction

4. What is an uncal herniation?
A: Herniation of the temporal lobe uncus under the tentorium cerebelli
herniation

5. What is the etiology of Tinea Versicolour?
A: Malassezia spp.
Malassezia furfur; Malassezia globosa; Malassezia sympodialis. Occurs in hot, humid weather.
Versicolour

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