Summary 1) Fundamentals of Pathology by Hussain Sattar
Patent Ductus Arteriosus (PDA) is the failure of the ductus arteriosus to close.
Pathophysiology 2) Wikipedia
The ductus arteriosus is a normal fetal blood vessel that closes soon after birth. In a PDA, the vessel does not close and remains patent (open) resulting in irregular transmission of blood between two of the most important arteries close to the heart, the aorta and the pulmonary artery. A PDA allows a portion of the oxygenated blood from the left heart to flow back to the lungs by flowing from the aorta (which has higher pressure) to the pulmonary artery. If this shunt is substantial, the neonate becomes short of breath: the additional fluid returning to the lungs increases lung pressure to the point that the neonate has greater difficulty inflating the lungs. This uses more calories than normal and often interferes with feeding in infancy. This condition, as a constellation of findings, is called congestive heart failure.
Causes 3) Rapid Review Pathology by Edward Goljan
- Common with Congenital Rubella, Respiratory Distress Syndrome and Complete Transposition
- Chronic Heart Failure
- Late Cyanosis in the lower extremities
- Machinery-like murmur throughout the cardiac cycle
- Doppler echocardiography – machinery-like murmur throughout the systole and diastole
Treatment 6)First Aid for the Basic Sciences: Organ Systems by Tao Le7)Rapid Review Pathology by Edward Goljan
- Surgical Closure
Comments 8) Fundamentals of Pathology by Hussain Sattar
- May lead to Eisenmenger syndrome
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