Summary 1) Robbins Basic Pathology by Vinay Kumar
Mallory-Weiss syndrome are bleeding which are often associated with severe retching or vomiting, as may occur with acute alcohol intoxication.
Pathophysiology 2) BMJ Publishing Group Limited
The pathogenesis of MWT is not completely understood. However, most cases seem to occur as a result of a sudden rise in abdominal pressure or transmural pressure gradient across the gastro-oesophageal junction. When these forces are high enough to cause distention in this poorly distended area, an acute gastro-oesophageal tear or laceration may occur.
Causes 3) Wikipedia
- Eating disorders
- Hiatal hernia
Symptoms 4) Healthline.com
- Abdominal pain
- Bloody stool
- Involuntary retching
- Severe vomiting
- Vomiting blood (a condition called “hematemesis”)
Diagnosis 5) Robbins Basic Pathology by Vinay Kumar
- Endoscopy – roughly linear lacerations of Mallory-Weiss syndrome are longitudinally oriented, range in length from millimeters to several centimeters, and usually cross the gastroesophageal junction.
Treatment 6) Wikipedia
- Cauterization or injection of epinephrine – to stop the bleeding may be undertaken during the index endoscopy procedure
- Embolization of the arteries supplying the region – may be required to stop the bleeding
- High gastrostomy – can be used to ligate the bleeding vessel
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