Angina Pectoris

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Summary 1) First Aid for the Basic Sciences: Organ Systems by Tao Le

Angina Pectoris is an episodic chest pain caused by a disparity between cardiac perfusion and cardiac demand leading to transient hypoxia of the myocardium.

Pathophysiology 2) Wikipedia

Diagram of the blockage causing angina (Medical Pictures Info)

Angina results when there is an imbalance between the heart’s oxygen demand and supply. This imbalance can result from an increase in demand (e.g., during exercise) without a proportional increase in supply (e.g., due to obstruction or atherosclerosis of the coronary arteries). However, the pathophysiology of angina in females varies significantly as compared to males. Non-obstructive coronary disease is more common in females.

Causes 3) First Aid for the Basic Sciences: Organ Systems by Tao Le

  • Inadequate cardiac perfusion

Symptoms 4) First Aid for the Basic Sciences: Organ Systems by Tao Le

  • Retrosternal chest pain or pressure that can radiate to the neck, jaw or left arm and lasts from 15 seconds to 15 minutes
  • Diaphoresis
  • Nausea

Diagram of site of pain radiation in angina (Jameda)

Diagnosis 5) First Aid for the Basic Sciences: Organ Systems by Tao Le

  • ECG  prior MI or ischemia
  • Stress Test  inducible ischemia 
  • Cardiac Catheterization  coronary obstruction

Treatment 6)First Aid for the Basic Sciences: Organ Systems by Tao Le7)Rapid Review Pathology by Edward Goljan

  • Modification of risk factors  losing weight, cessation of smoking, low cholesterol diet and exercise
  • Medications  Nitrates, β-blockers and Calcium Channel Blockers
  • Surgery  Coronary Artery Bypass Graft and Percutaneous Transluminal Coronary Angioplasty

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